Writing & Research
Zenodo (v1) · Open source on GitHub · Mar 2026

NeoRx: Causal Inference for Automated Drug Target Identification via Pearl's Do-Calculus over Multi-Source Biomedical Knowledge Graphs

End-to-end causal pipeline applying Pearl's do-calculus across 8 biomedical knowledge graphs. SMILES BiGRU VAE (4.1M params, 97% validity), hierarchical RL (UCB1 + CEM), AutoDock Vina docking. Mean F₁ = 0.474 across 7 disease validations with zero false positives.

Causal inferenceKnowledge graphsDrug discovery

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